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CYTOCHROME-B(5) REDUCTASE
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DeCS
Descriptor
Inglés
:
Cytochrome-B(5) Reductase
Descriptor
Español
:
Citocromo-B(5) Reductasa
Descriptor
Portugués
:
Citocromo-B(5) Redutase
Categoría:
D08.811.682.608.191.237
D12.776.331.186
Definición
Inglés
:
A FLAVOPROTEIN oxidoreductase that occurs both as a soluble enzyme and a membrane-bound enzyme due to
ALTERNATIVE SPLICING
of a single mRNA. The soluble form is present mainly in
ERYTHROCYTES
and is involved in the reduction of
METHEMOGLOBIN
. The membrane-bound form of the enzyme is found primarily in the
ENDOPLASMIC RETICULUM
and outer mitochondrial membrane, where it participates in the desaturation of
FATTY ACIDS
;
CHOLESTEROL
biosynthesis and drug
metabolism
. A deficiency in the enzyme can result in
METHEMOGLOBINEMIA.
Nota de Indización
Inglés
:
/defic: consider also
METHEMOGLOBINEMIA
Nota Histórica
Inglés
:
2004; use CYTOCHROME B(5) REDUCTASE (NM) 1980-2003
Calificadores Permitidos
Inglés
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número del Registro:
38212
Identificador Único:
D042966
Ocurrencia en la BVS
:
Similar:
DeCS
CID-10
SciELO
LILACS
LIS